The 2025 Apertura Tournament of Santiago del Estero has defined the matchups for the round of 16, quarter-finals, and semi-finals, as well as the venue for the grand final. The home advantage in the previous stages will go to the team ranked highest in the regular phase, while the final will be held at the Único Madre de Ciudades Stadium in Santiago del Estero.
The playoff matchups for the 2025 Apertura Tournament are as follows: Argentinos vs. Instituto, San Lorenzo vs. Tigre, River vs. Barracas Central, Racing vs. Platense, Rosario Central vs. Estudiantes, Huracán vs. Deportivo Riestra, Boca vs. Lanús, and Independiente vs. Independiente Rivadavia.
If they advance through the rounds, interesting classics could occur in the quarter-finals such as Boca vs. Racing and River vs. Independiente. In a hypothetical semi-final, there could be a matchup between Argentinos and Platense. The Superclásico, between Boca and River, could only happen in a potential final, just like an Avellaneda classic or a confrontation between Huracán and San Lorenzo.
The competition reaches its decisive stages following the conclusion of matchday 16, with the 16 qualified teams and the round of 16 matchups already determined. These eliminations will be played in a single match, adding excitement and tension to each game of the 2025 Apertura Tournament.
